If you don’t know programming… specifically Python… you’re probably scratching your head at this one.  I tried to make a feature of Python understandable to non-programmers.  Not sure if I succeeded.
Basically a “while-loop” is a chunk of code that keeps repeating until a specific condition changes.  Like if a boolean ( a True or False) switches states… from a True to a False, or vice versa.
In this strip, I trick Ms. Boolean into giving the command to stop the while-loop. 
Is it funny?  I dunno.
Is it clever?  I think so.
But, you be the judge.
John Vogel